abstract：:Although attempts have been made to reveal the relationships between bacteria and human health, little is known about the species and function of the microbial community associated with oral diseases. In this study, we report the sequencing of 16 metagenomic samples collected from dental swabs and plaques representing...

journal_title：Scientific reports

authors： Wang J,Qi J,Zhao H,He S,Zhang Y,Wei S,Zhao F

更新日期：2013-01-01 00:00:00

abstract：:ING2 (inhibitor of growth family member 2) is a component of a chromatin-regulatory complex that represses gene expression and is implicated in cellular processes that promote tumor suppression. However, few direct genomic targets of ING2 have been identified and the mechanism(s) by which ING2 selectively regulates ge...

journal_title：Scientific reports

authors： Bua DJ,Martin GM,Binda O,Gozani O

更新日期：2013-01-01 00:00:00

abstract：:In the study, we analyzed role of p53 in predicting outcome in visceral metastasis breast cancer (VMBC) patients. 97 consecutive VMBC patients were studied. P53 positivity rate was 29.9%. In the p53-negative group, median disease free survival (DFS), and time from primary breast cancer diagnosis to death (OS1), time f...

journal_title：Scientific reports

authors： Yang P,Du CW,Kwan M,Liang SX,Zhang GJ

更新日期：2013-01-01 00:00:00

abstract：:Biological validation of new radiotherapy modalities is essential to understand their therapeutic potential. Antiprotons have been proposed for cancer therapy due to enhanced dose deposition provided by antiproton-nucleon annihilation. We assessed cellular DNA damage and relative biological effectiveness (RBE) of a cl...

journal_title：Scientific reports

authors： Kavanagh JN,Currell FJ,Timson DJ,Savage KI,Richard DJ,McMahon SJ,Hartley O,Cirrone GA,Romano F,Prise KM,Bassler N,Holzscheiter MH,Schettino G

更新日期：2013-01-01 00:00:00

abstract：:Based on an inverted bulk band order, antimony thin films presumably could become topological insulators if quantum confinement effect opens up a gap in the bulk bands. Coupling between topological surface states (TSS) from opposite surfaces, however, tends to degrade or even destroy their novel characters. Here the e...

journal_title：Scientific reports

authors： Yao G,Luo Z,Pan F,Xu W,Feng YP,Wang XS

更新日期：2013-01-01 00:00:00

abstract：:Luminance plays a modulating role in the processes of several visual tasks, which in turn provides significant information for the understanding of visual processing. Here, using a binocular phase combination paradigm, we studied the effect of unilateral changes in mean luminance on binocular combination in both norma...

journal_title：Scientific reports

authors： Zhou J,Jia W,Huang CB,Hess RF

更新日期：2013-01-01 00:00:00

abstract：:The recent emergence of highly virulent human adenoviruses (HAdVs) with new tissue tropisms underscores the need to determine their ontogeny. Here we report complete high quality genome sequences and analyses for all the previously unsequenced HAdV serotypes (n = 20) within HAdV species D. Analysis of nucleotide seque...

journal_title：Scientific reports

authors： Robinson CM,Singh G,Lee JY,Dehghan S,Rajaiya J,Liu EB,Yousuf MA,Betensky RA,Jones MS,Dyer DW,Seto D,Chodosh J

更新日期：2013-01-01 00:00:00

abstract：:From the viewpoint of networks, a ranking system for players or teams in sports is equivalent to a centrality measure for sports networks, whereby a directed link represents the result of a single game. Previously proposed network-based ranking systems are derived from static networks, i.e., aggregation of the results...

journal_title：Scientific reports

authors： Motegi S,Masuda N

更新日期：2012-01-01 00:00:00

abstract：:Solitons are of fundamental importance in photonics due to applications in optical data transmission and also as a tool for investigating novel phenomena ranging from light generation at new frequencies and wave-trapping to rogue waves. Solitons are also moving scatterers: they generate refractive index perturbations ...

journal_title：Scientific reports

authors： Rubino E,Lotti A,Belgiorno F,Cacciatori SL,Couairon A,Leonhardt U,Faccio D

更新日期：2012-01-01 00:00:00

abstract：:A previous study identified 3 nonsynonymous and 6 synonymous mutations in the entire mosquito sodium channel of Culex quinquefasciatus, the prevalence of which were strongly correlated with levels of resistance and increased dramatically following insecticide selection. However, it is unclear whether this is unique to...

journal_title：Scientific reports

authors： Li T,Zhang L,Reid WR,Xu Q,Dong K,Liu N

更新日期：2012-01-01 00:00:00

abstract：:Conventional spin-singlet Cooper pairs convert into spin-triplet pairs in ferromagnetic Josephson junctions in which the superconductor/ferromagnet interfaces (S/F) are magnetically inhomogeneous. Although much of the theoretical work describing this triplet proximity effect has considered ideal junctions with magneti...

journal_title：Scientific reports

authors： Robinson JW,Chiodi F,Egilmez M,Halász GB,Blamire MG

更新日期：2012-01-01 00:00:00

abstract：:Polymer electrolyte membranes (PEM) and Pt-based catalysts are two crucial components which determine the properties and price of fuel cells. Even though, PEM faces problem of fuel crossover in liquid fuel cells such as direct methanol fuel cell (DMFC) and direct borohydride fuel cell (DBFC), which lowers power output...

journal_title：Scientific reports

authors： Yang X,Liu Y,Li S,Wei X,Wang L,Chen Y

更新日期：2012-01-01 00:00:00

abstract：:Traditional strengthening ways, such as strain, precipitation, and solid-solution, come into effect by pinning the motion of dislocation. Here, through first-principles calculations we report on an extra-electron induced covalent strengthening mechanism, which alters chemical bonding upon the introduction of extra-val...

journal_title：Scientific reports

authors： Niu H,Chen XQ,Liu P,Xing W,Cheng X,Li D,Li Y

更新日期：2012-01-01 00:00:00

abstract：:Routers, switches, and repeaters are essential components of modern information-processing systems. Similar devices will be needed in future superconducting quantum computers. In this work we investigate experimentally the time evolution of Autler-Townes splitting in a superconducting phase qubit under the application...

journal_title：Scientific reports

authors： Li J,Paraoanu GS,Cicak K,Altomare F,Park JI,Simmonds RW,Sillanpää MA,Hakonen PJ

更新日期：2012-01-01 00:00:00

abstract：:Silicon is the second most common element on the Earth's crust and its oxide (SiO(2)) the most abundant mineral. Silica and silicates are widely used in medicine and industry as well as in micro- and nano-optics and electronics. However, the fabrication of glass fibres and components requires high temperature and non-...

journal_title：Scientific reports

authors： Polini A,Pagliara S,Camposeo A,Cingolani R,Wang X,Schröder HC,Müller WE,Pisignano D

更新日期：2012-01-01 00:00:00

abstract：:Influenza infection represents a major socio-economic burden worldwide. Novel delivery methods can render influenza vaccination easier and more acceptable by the public, and importantly confer protection equal or superior to that induced by conventional systemic administration. An attractive target for vaccine deliver...

journal_title：Scientific reports

authors： Koutsonanos DG,Vassilieva EV,Stavropoulou A,Zarnitsyn VG,Esser ES,Taherbhai MT,Prausnitz MR,Compans RW,Skountzou I

更新日期：2012-01-01 00:00:00

abstract：:Humans bargaining over money tend to reject unfair offers, whilst chimpanzees bargaining over primary rewards of food do not show this same motivation to reject. Whether such reciprocal fairness represents a predominantly human motivation has generated considerable recent interest. We induced either moderate or severe...

journal_title：Scientific reports

authors： Wright ND,Hodgson K,Fleming SM,Symmonds M,Guitart-Masip M,Dolan RJ

更新日期：2012-01-01 00:00:00

abstract：:Understanding and mitigating decoherence is a key challenge for quantum science and technology. The main source of decoherence for solid-state spin systems is the uncontrolled spin bath environment. Here, we demonstrate quantum control of a mesoscopic spin bath in diamond at room temperature that is composed of electr...

journal_title：Scientific reports

authors： de Lange G,van der Sar T,Blok M,Wang ZH,Dobrovitski V,Hanson R

更新日期：2012-01-01 00:00:00

abstract：:A singular adaptive phenotype of a parthenogenetic insect species (Acyrthosiphon pisum) was selected in cold conditions and is characterized by a remarkable apparition of a greenish colour. The aphid pigments involve carotenoid genes well defined in chloroplasts and cyanobacteria and amazingly present in the aphid gen...

journal_title：Scientific reports

authors： Valmalette JC,Dombrovsky A,Brat P,Mertz C,Capovilla M,Robichon A

更新日期：2012-01-01 00:00:00

abstract：:Gene targeting in embryonic stem cells (ESCs) has become the principal technology for generating knockout models. Although numerous studies have predicted that the disruption of p53 leads to increased developmental anomalies and malignancies, most p53 knockout mice develop normally. Therefore, the role of p53 in anima...

journal_title：Scientific reports

authors： Kawamata M,Ochiya T

更新日期：2012-01-01 00:00:00

abstract：:A variety of animals use Earth's magnetic field as a reference for their orientation behaviour. Although distinctive magnetoreception mechanisms have been postulated for many migrating or homing animals, the molecular mechanisms are still undefined. In this study, we found that zebrafish, a model organism suitable for...

journal_title：Scientific reports

authors： Takebe A,Furutani T,Wada T,Koinuma M,Kubo Y,Okano K,Okano T

更新日期：2012-01-01 00:00:00

abstract：:Visible indication based on the aggregation of colloidal nanoparticles (NPs) is highly advantageous for rapid on-site detection of biological entities, which even untrained persons can perform without specialized instrumentation. However, since the extent of aggregation should exceed a certain minimum threshold to pro...

journal_title：Scientific reports

authors： Lim S,Koo OK,You YS,Lee YE,Kim MS,Chang PS,Kang DH,Yu JH,Choi YJ,Gunasekaran S

更新日期：2012-01-01 00:00:00

abstract：:Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy. We found significant reductions in litter size and foetal weight in Anxa5-null...

journal_title：Scientific reports

authors： Ueki H,Mizushina T,Laoharatchatathanin T,Terashima R,Nishimura Y,Rieanrakwong D,Yonezawa T,Kurusu S,Hasegawa Y,Brachvogel B,Pöschl E,Kawaminami M

更新日期：2012-01-01 00:00:00

abstract：:A method is proposed to drive an ultrafast non-adiabatic dynamics of an ultracold gas trapped in a time-dependent box potential. The resulting state is free from spurious excitations associated with the breakdown of adiabaticity, and preserves the quantum correlations of the initial state up to a scaling factor. The p...

journal_title：Scientific reports

authors： del Campo A,Boshier MG

更新日期：2012-01-01 00:00:00

abstract：:Assembly of nanowires into ordered macroscopic structures with new functionalities has been a recent focus. In this Letter, we report a new route for ordering hydrophilic Ag nanowires with high aspect ratio by flowing through a glass capillary. The present glass capillary with well-defined silver nanowire films inside...

journal_title：Scientific reports

authors： Liu JW,Wang JL,Huang WR,Yu L,Ren XF,Wen WC,Yu SH

更新日期：2012-01-01 00:00:00

abstract：:Successful immunity requires that a limited pool of αβ T-cell receptors (TCRs) provide cover for a vast number of potential foreign peptide antigens presented by 'self' major histocompatibility complex (pMHC) molecules. Structures of unligated and ligated MHC class-I-restricted TCRs with different ligands, supplemente...

journal_title：Scientific reports

authors： Holland CJ,Rizkallah PJ,Vollers S,Calvo-Calle JM,Madura F,Fuller A,Sewell AK,Stern LJ,Godkin A,Cole DK

更新日期：2012-01-01 00:00:00

abstract：:There are a number of psychological phenomena in which dramatic emotional responses are evoked by seemingly innocuous perceptual stimuli. A well known example is the 'uncanny valley' effect whereby a near human-looking artifact can trigger feelings of eeriness and repulsion. Although such phenomena are reasonably well...

journal_title：Scientific reports

authors： Moore RK

更新日期：2012-01-01 00:00:00

abstract：:We analyze a transition from single peaked to bimodal velocity distribution in a relativistic fluid under increasing temperature, in contrast with a non-relativistic gas, where only a monotonic broadening of the bell-shaped distribution is observed. Such transition results from the interplay between the raise in therm...

journal_title：Scientific reports

authors： Mendoza M,Araújo NA,Succi S,Herrmann HJ

更新日期：2012-01-01 00:00:00

abstract：:A gas of magnons in magnetic films differs from all other known systems demonstrating Bose-Einstein condensation (BEC), since it possesses two energetically degenerate lowest-energy quantum states with non-zero wave vectors ±k(BEC). Therefore, BEC in this system results in a spontaneously formed two-component Bose-Ein...

journal_title：Scientific reports

authors： Nowik-Boltyk P,Dzyapko O,Demidov VE,Berloff NG,Demokritov SO

更新日期：2012-01-01 00:00:00

abstract：:Microsecond (μs) time-resolved extended X-ray absorption fine structure spectroscopy (EXAFS) has been developed using an energy-dispersive EXAFS (EDE) setup equipped with a silicon Quantum Detector ULTRA. The feasibility was investigated with a prototypical thermally driven redox reaction, the thermal decomposition of...

journal_title：Scientific reports

authors： Kong Q,Baudelet F,Han J,Chagnot S,Barthe L,Headspith J,Goldsbrough R,Picca FE,Spalla O

更新日期：2012-01-01 00:00:00

abstract：:Mechanistic exploration of the origins of the unparalleled soil microbial biodiversity represents a vast and uncharted scientific frontier. Quantification of candidate mechanisms that promote and sustain such diversity must be linked with microbial functions and measurable biophysical interactions at appropriate scale...

journal_title：Scientific reports

authors： Wang G,Or D

更新日期：2012-01-01 00:00:00

abstract：:Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomic analysis. We foun...

journal_title：Scientific reports

authors： Kim J,Kim I,Han SK,Bowie JU,Kim S

更新日期：2012-01-01 00:00:00

abstract：:Schistosomes, unlike malaria parasites, are in their diploid stage when targeted by the human immune system. Diploids can be either homozygous or heterozygous. The difference has profound significance for developing immunity and yet has not previously been addressed. We examined the implications of zygosity on immunit...

journal_title：Scientific reports

authors： Xu X,Sun J,Zhang J,Wellems D,Qing X,McCutchan T,Pan W

更新日期：2012-01-01 00:00:00

abstract：:The transcription apparatus (TA) is a huge molecular machine. It detects the time-varying concentrations of transcriptional activators and initiates mRNA transcripts at appropriate rates. Based on the general structural organizations of the TA, we propose how the TA dynamically orchestrates transcriptional responses. ...

journal_title：Scientific reports

authors： Wang Y,Liu F,Wang W

更新日期：2012-01-01 00:00:00

abstract：:Centenarians exhibit extreme longevity and a remarkable compression of morbidity. They have a unique capacity to maintain homeostatic mechanisms. Since small non-coding RNAs (including microRNAs) are implicated in the regulation of gene expression, we hypothesised that longevity of centenarians may reflect alterations...

journal_title：Scientific reports

authors： Serna E,Gambini J,Borras C,Abdelaziz KM,Belenguer A,Sanchis P,Avellana JA,Rodriguez-Mañas L,Viña J

更新日期：2012-01-01 00:00:00

abstract：:Highly efficient and specific biomolecular recognition requires both affinity and specificity. Previous quantitative descriptions of biomolecular recognition were mostly driven by improving the affinity prediction, but lack of quantification of specificity. We developed a novel method SPA (SPecificity and Affinity) ba...

journal_title：Scientific reports

authors： Yan Z,Wang J

更新日期：2012-01-01 00:00:00

abstract：:Agriculture resulted in extensive population growths and human activities. However, whether major human expansions started after Neolithic Time still remained controversial. With the benefit of 1000 Genome Project, we were able to analyze a total of 910 samples from 11 populations in Africa, Europe and Americas. From ...

journal_title：Scientific reports

authors： Zheng HX,Yan S,Qin ZD,Jin L

更新日期：2012-01-01 00:00:00

abstract：:Carbon fiber-synthetic foam core sandwich composites are widely used for many structural applications due to their superior mechanical performance and low weight. Unfortunately these structures typically have very poor acoustic performance. There is increasingly growing demand in mitigating this noise issue in sandwic...

journal_title：Scientific reports

authors： Sargianis J,Kim HI,Suhr J

更新日期：2012-01-01 00:00:00

abstract：:Altered death receptor signaling and resistance to subsequent apoptosis is an important clinical resistance mechanism. Here, we investigated the role of death receptor resistance in breast cancer progression. Resistance of the estrogen receptor alpha (ER)-positive, chemosensitive MCF7 breast cancer cell line to tumor ...

journal_title：Scientific reports

authors： Antoon JW,Lai R,Struckhoff AP,Nitschke AM,Elliott S,Martin EC,Rhodes LV,Yoon NS,Salvo VA,Shan B,Beckman BS,Nephew KP,Burow ME

更新日期：2012-01-01 00:00:00

abstract：:The risk of Helicobacter pylori infection is highest in childhood, but the colonization process of the stomach mucosa is poorly understood. We used anesthetized Mongolian gerbils to study the initial stages of H. pylori colonization. Prandial and postprandial gastric conditions characteristic of humans of different ag...

journal_title：Scientific reports

authors： Bücker R,Azevedo-Vethacke M,Groll C,Garten D,Josenhans C,Suerbaum S,Schreiber S

更新日期：2012-01-01 00:00:00